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In reality, treatment often begins with conservative strategies aimed at improving function, reducing pain, and maintaining mobility for as long as possible

Doctors can just as easily be blind to it in people even though B12 deficiency is a common health problem that affects an estimated 6% to 20% of the U.S

For longer-term research, intermittent dosing schedules may be more practical, with adjustments to the dose amount per administration to achieve the desired cumulative exposure

Required evidence may include clinical studies, extensive post-marketing use data, expert advice, and the views of relevant health professionals and public associations