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Less food means less fuel, and tiredness is a predictable result

The preclinical studies examined in the review explored how GLP-1RAs influence the brain, specifically, its role in reducing inflammation, protecting neurons from damage, enhancing synaptic functioning, and improving insulin signaling within the brain

Here, we demonstrate that the effects of cotadutide in reducing body weight and food intake and improving glucose control are predominantly mediated through Glp-1 signalling, whereas its action on the liver to reduce lipid content, drive glycogen flux and improve mitochondrial turnover and function are directly mediated through Gcg signalling

Drink one serving before a workout