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Prescription of guideline-directed medical therapies in patients with diabetes and chronic kidney disease from the CURE-CKD Registry, 2019-2020

Type 2 diabetes is a complex disease and the significant glucose control and weight loss achieved with once-weekly semaglutide compared with dulaglutide are encouraging, as more treatment options are needed. Safety Safety profiles were similar between patients given semaglutide and dulaglutide, and less than 10% of patients had to discontinue therapy prematurely due to adverse events across all treatment groups

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That same body of work also shows meaningful weight outcomes: in one study of 500 patients, 75% reported significant weight loss with semaglutide, and these changes drive downstream shifts in lipids and cardiovascular markers