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Lignans from flaxseed, converted to enterolactone (EL) and enterodiol by gut microflora within the intestines, possess weak estrogenic activity that competes with endogenous oestrogens for ER binding causing decreased mitogenic stimulation and lower circulating estrogen concentrations via upregulation of sex hormonebinding globulin (SHBG) (189, 190)

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Changes in activities of creatine-synthetic enzymes in tissues of hybrid striped bass fed a soybean meal (58%)-based diet supplemented with 0, 1%, or 2% glycine

The synthetic version used in research and by the peptide community is a stable fragment of this naturally occurring compound