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Patient selection should consider contraindications including personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 for specific agents (liraglutide, semaglutide, dulaglutide, tirzepatide), as these carry a boxed warning based on rodent thyroid C-cell tumor findings
All these side effects are temporary and relatively minor
2015 Dec;102(6):1357-64
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