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[5] [6] For weight management, NICE technology appraisals (TA664 for semaglutide/Wegovy and TA662 for liraglutide/Saxenda) recommend use only within specialist weight management services for people meeting specific BMI thresholds with weight-related comorbidities
While traditional weight loss therapies typically target just one hormonal pathway or rely solely on appetite suppression, Tirzepatide simultaneously activates two vital hormone receptors in the bodyGLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide)
How does Ozempic compare with Wegovy or Mounjaro
Diabetes 61 , 888896 (2012)
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