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In the context of constitutive HIF-2 stabilization 75 or a defective mitochondrial electron transport chain 76 , glutamine-derived -KG is reductively carboxylated through the consumption of NADPH by IDH2 to generate citrate
T.ZhongF.HeY.et al (2023)
Une bonne et efficace coordination de ces systmes est cruciale pour viter une carence en glutathion et garantir qu'une quantit suffisante de glutathion actif soit disponible
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