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In this model, insulin signaling is much reduced in the brain by STZ, and tau phosphorylation is enhanced

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This approach of senescent T-cells elimination has a great potential to restore immune system function and therefore, to protect the aged animal against numerous aging-associated disorders 70

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CrossRef Adipokines at the crossroad between obesity and cardiovascular disease Filippo Molica, Sandrine Morel, Brenda Kwak, Franoise Rohner-Jeanrenaud, Sabine Steffens Thrombosis and Haemostasis.2015

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Fanelli, et al

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