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Being overweight or obese places you at risk for a wide range of health conditions including heart disease, diabetes, stroke, sleep apnea, and mental health conditions like depression and anxiety [2]
Nf1-deficient mouse Schwann cells are angiogenic and invasive and can be induced to hyperproliferate: reversion of some phenotypes by an inhibitor of farnesyl protein transferase
Furthermore, vagotomy abolishes the effect of GLP-1 on food intake, while more selective subdiaphragmatic vagal deafferentation attenuates the inhibitory effect of higher doses of intraperitoneal GLP-1 (100 nmol/kg) 136
