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We acknowledge that classification of gastrointestinal AEs, such as nausea, vomiting, diarrhea, constipation, dyspepsia, and reduced appetite, may vary across studies, which could introduce some heterogeneity in the reported incidences

Researchers at the University of California, San Diego and several partner institutions analyzed data from a previously published clinical trial of 108 adults with HIVassociated lipohypertrophy, a condition in which excess fat builds up around the abdomen

However, severe bloating paired with vomiting, intense pain, or inability to eat or drink warrants immediate medical attention

This mechanism reduces the risk of hypoglycaemia when used alone, though this risk increases significantly when combined with insulin or sulphonylureas