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Health Canada said it met its target timeline of six months because it doesnt include the time required for the company to provide additional data or information requested by the department

Before reaching the target dose, a typical dosing schedule may look like the following: Month 1: 2.5 mg once weekly for the first month Month 2: 5 mg once weekly for the second month Month 3: 7.5 mg once weekly for the third month Month 4: 10 mg once weekly for the fourth month Month 5: 12.5 mg once weekly for the fourth month Target maintenance dose: 15 mg once weekly Depending on whether or not there are any experienced side-effects may change the dosing schedule for some individuals

Your provider should reassess your B12 levels periodically typically every 3 to 6 months to determine whether continued injections are warranted or whether oral supplementation is sufficient to maintain adequate levels

Of note, the effect of SGLT2 inhibitors on hospitalization for heart failure or cardiovascular death (HR, 0.77