MC1R is expressed on keratinocytes, fibroblasts, dendritic cells, mast cells, and other immune cells in the skin , and MT-1-mediated MC1R activation produces anti-inflammatory effects in these cell types through cAMP-mediated suppression of NF-B activation, reduction of pro-inflammatory cytokine production including TNF-alpha and IL-6, inhibition of reactive oxygen species generation, and modulation of dendritic cell maturation and antigen presentation
Its crucial in many biological processes, including metabolism, DNA repair, and cell signaling
External links [edit] Media related to Peter Attia at Wikimedia Commons 1973 births Living people 21st-century American non-fiction writers 21st-century Canadian non-fiction writers American health and wellness writers American male non-fiction writers American medical writers American writers of Egyptian descent Canadian health and wellness writers Canadian male non-fiction writers Canadian people of Egyptian descent Health professionals from Toronto Life extensionists Longevity researchers Preventive medicine Queen's University at Kingston alumni Stanford University School of Medicine alumni Writers from Austin, Texas Writers from Ontario Writers from Toronto
Other ingredients Microcrystalline cellulose, hypromellose (vegetarian capsule), silica