Nakamura H, Horai Y, Suzuki T, Okada A, Ichinose K, Yamasaki S, et al
A direct correlation between increased metabolism of docetaxel, flutamide, paclitaxel, and mitoxantrone because of increased expression of CYP1B1 (cytochrome P450 1B1) and the onset of MDR in various cancer cells has been drawn out by researchers, as is the case with overexpression of the CYP2A6 (cytochrome P450 2A6) enzyme in breast tumour cells, whereby it is reported to enhance the metabolism of drugs like aflatoxin, cyclophosphamide, ifosfamide, and fluorouracil [54]
It is the kind of reasoning that sounds plausible on paper and has not been put to a controlled test
Food and Drug Administration (FDA)-approved for weight loss, healthcare providers may prescribe Ozempic for weight loss off-label