semaglutide average weight loss first month on Month: What to Expect Long-term weight loss effects of

FDA "Compounding and the FDA: Questions and Answers" (regulatory status of compounded medications): fda.gov/drugs/human-drug-compounding/compounding-and-fda-questions-and-answers New England Journal of Medicine STEP 1 (Wilding et al., 2021)

They target weight loss through completely different mechanisms

4.11 SURMOUNT-CN: tirzepatide for weight loss in Chinese obese and overweight adults The SURMOUNT-CN trial recruited 210 obese or overweight adult patients in China, who received weekly doses of tirzepatide (10 mg, 15 mg) or placebo for 52 weeks

Patients should be aware of important safety considerations, including risks of pancreatitis, gallbladder disease, and potential worsening of diabetic retinopathy (particularly with rapid improvement in blood glucose)