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Among the main differences between liraglutide and semaglutide lies in their dosing schedules and specific effects on weight loss, with liraglutide requiring daily administration and semaglutide taken once a week

Messer says, the amount of weight loss well see clinically with retatrutide will probably exceed what researchers saw in the trial. Some doctors tell me they expect the drug to outperform even bariatric surgery, leading to more weight loss in less time