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When this joint becomes inflamed or misaligned, it can cause pain that radiates to the ear, especially during jaw movement like chewing or talking

Ongoing pressure keeps stress hormones elevated, which over time can affect sleep, digestion, blood pressure, and the immune system, so calming the mind alone is rarely enough

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The human results are mixed, with small open-label studies encouraging but the controlled phase 2 OVERTURE trial missing its primary endpoint, and the larger pivotal trial has finished enrolling with results pending, so for now it is best read as mechanistically promising and clinically unproven