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Studies have shown that 6MP has a short plasma half-life of between 1 and 2 h and is quickly removed via the renal system

IHC analysis revealed that VDAC1 expression was significantly higher in GC patients with PTX resistance compared to PTX-sensitive patients

13 The very high, sustained, and non-physiological levels of exogenous GLP-1 resulting from the administration of these agents may likely explain both some of the mode of action and the adverse effects of GLP-1 RAs