what are the long term side effects of tirzepatide long-term Thinking about Semaglutide or Tirzepatide? Let's talk honestly. 🙋 Because Long-Term Side Effects of Zepbound:

Like many metabolic conditions, the underlying factors that contribute to weight gain do not disappear

The beneficial effects of GLP-1 RAs on HRQoL and other outcomes in HFpEF are likely due to pleiotropic impacts, related or not to weight reduction, such as decongestion (mainly due to the reduction of increased plasma volume associated with obesity and epicardial constrain), reverse cardiac remodelling (mainly due to the decrease in epicardial fat and regression of left atrial and LV myopathy, lowering intracardiac pressure) and anti-inflammatory actions, among others

off-label use is needed

Proper storage between 36 to 46F (2 to 8C) is necessary to maintain effectiveness