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doi:10.1136/bmjdrc-2020-001856 Horikawa C, Aida R, Kamada C, et al
Emerging role of AMPK in brown and beige adipose tissue (BAT): implications for obesity, insulin resistance, and type 2 diabetes
Interestingly, tirzepatide, a dual-acting GIP/GLP-1 receptor agonist that is now clinically approved for both obesity and T2D, was designed with an amino acid sequence closely resembling that of native GIP, resulting in strong preference for GIPR binding over the GLP-1R
If you fall into this category, the timing of your dose can influence its effectiveness
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