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Unlike the controls, patients with Wilson disease showed significantly increased plasma levels of T helper (Th) 1 cytokines (IL-2, TNF-, and TNF-), Th2 cytokines (IL-5, IL-10, and IL-13), and Th17 cytokines (IL-23)

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When B12 levels are low, the body may not produce enough healthy red blood cells to carry oxygen throughout the body

On the basis of these studies, the capacity of HGF to modulate neuro-inflammation is thus associated with an alteration in the balance of pro-inflammatory (Th1 and Th17) and anti-inflammatory (Th2 and Tregs) CD4 + T cells by influencing dendritic cell function