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Afamelanotide is authorised in the regulated Scenesse implant for preventing phototoxicity in adults with erythropoietic protoporphyria
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration
In view of the pivotal role played by GSH in redox system and the relationship between oxidative stress and autophagy 68 , it is conceivable that GSH depletion-induced oxidative stress and lipid peroxidation may be a key point linking ferroptosis and autophagy in RPE cells
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