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In another hand, it is notable that the role of GH, if any, on the regulation of intratesticular IGF-I may not be significant, since GH receptor gene may not be expressed in the testis[134, 135] and GHI animals are fertile (normal steroidogenesis and spermatogenesis)[136, 137]
Despite these limitations, we believe that our finding of an inverse association between OBS and incident HTN in a large population-based prospective cohort study is informative
Its defining property is receptor selectivity at typical research doses it produces minimal cortisol, prolactin, or ACTH elevation, distinguishing it from earlier GHRPs like GHRP-6 or GHRP-2
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