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We can enhance the anti-tumour capacities of neutrophils by interfering with innate immune inhibitory checkpoints to restore antibody-mediated anti-tumour activities, by targeting proteins downstream of the inhibitory receptor, by using IgA-based therapeutic mAbs that bind to the activating Fc receptors, and by modifying the Fc region of IgG therapeutic antibodies that increases affinity to Fc receptors, as shown in Figure 6 (53)
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(2018) 16:e2002864
therefore GSH/GSSG ratio is critical indicator of the health of cell
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