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As controls for the synergistic combination of ceftazidime/avibactam (AVI/CAZ), each component was also used at the lower concentration present in the combination as well as higher concentrations that individually inhibited 2030% of growth

Intracellularly, mainly in adipose tissue, its antioxidant action is limited, thus uric acid could interact with other radicals, and this could initiate a cascade of reactions to generate superoxide forms

Together these changes indicate that while fatty acid breakdown is upregulated to meet energy demands, fat synthesis via malonyl-CoA is likely reduced in gonadal tissue under starvation

Intakes above this level can cause copper deficiency over time