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Immune Function Growth hormone influences immune cell proliferation, thymic function, and inflammatory regulation

A phase 2 randomised controlled trial published in the New England Journal of Medicine (2023) reported substantial weight loss and improvements in glycaemic parameters, though the trial was conducted in a closely monitored clinical setting with defined eligibility criteria

Medical Contraindications People with a history of pancreatitis, thyroid cancer, certain mood disorders, or cardiovascular disease may not be suitable candidates for all medications

mechanisms proposed include NO modulation and angiogenesis