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Upon activation, phosphorylated MLKL (p-MLKL) oligomerizes and translocates to the cell membrane, forming pores that disrupt electrochemical gradients, resulting in lytic cell rupture and the release of damage-associated molecular patterns (DAMPs), inflammatory cytokines and chemokines

The soreness experienced after injecting Ozempic into the arm typically results from the mechanical trauma of needle insertion and the subsequent inflammatory response triggered by the introduction of the medication into subcutaneous tissue

Subsequently, by binding to C3a receptors, C3 causes neuronal dysfunction and microglial activation [27]

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