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"This portfolio of publications, derived from three major trials, significantly advances our understanding of the wide-ranging benefits of GLP-1 agonists, while also highlighting key questions that remain," said JACC Editor-in-Chief Harlan Krumholz, MD, SM, FACC
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A double-blind trial of a glucomannan, inulin, and psyllium blend reported a 4.9 percent treatment difference over 180 days, but with a 74.6 percent rate of (mostly mild and transient) gastrointestinal adverse events versus none on placebo, which underlines that GI tolerability, driven by viscosity and fermentation, is the central fiber formulation challenge [5]
The monkeys were assigned to seven groups ( n = 10 monkeys per group) with equal distribution of blood chemistries and BW
