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Step 4: Stool softeners and lubricants Docusate sodium (Colace) 100-200 mg twice daily Mineral oil 15-30 mL daily (oral or rectal) Stool softeners are the least effective option for GLP-1 constipation because the primary problem is motility, not stool hardness

However, long-term weight maintenance is more successful when exercise is included, as stopping GLP-1 therapy alone often leads to weight regain, while exercise helps preserve muscle mass and sustain weight loss

Get personalised guidance Because GLP-1 medications change your appetite and digestion, it is easy to under-eat or repeat the same limited foods

It depends on your eating habit, intensity of training and body-type