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The mechanism and result are similar to that of GSTP and JNK, in that GSTM1 sequesters ASK1 through complex formation and prevents its induction of the pro-apoptotic p38 and JNK portions of the MAPK signaling cascade
RCC2Rac1 complex formation prevents guanine nucleotide exchange factor (GEF)-mediated activation of Rac1, attenuating its activity outside protrusions 49
PMID 30626145
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