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In a comprehensive clinical overview, researchers explain that this buffering system prevents the toxic accumulation of unoxidized, short-chain acyl groups within the mitochondria

1 Mitochondrial physiology and mitochondrial diseases Mitochondria, essential organelles in eukaryotic cells, produce energy by generating adenosine triphosphate (ATP) through oxidative phosphorylation (OXPHOS)

Even if such associations are not found to be causal, a plausible explanation for the association itself could yet yield further insights into the metabolism of homocysteine