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The microbiome is a living dynamic environment where the relative abundance of species may fluctuate daily, weekly, and monthly depending on diet, medication, exercise, and a host of other environmental exposures (Monda et al., 2017
The medication slows alcohol metabolism by 30-50%, increases blood alcohol concentrations by 20-40%, and extends intoxication duration
If conservative measures fail after 46 weeks, or if specific pathology is identified, referral to appropriate specialists (physiatry, orthopedics, neurosurgery, pain management, or rheumatology) may be warranted
This is due to their durability and resistance to bending or breaking during use
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