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The TPH2 gene is located on chromosome 12q21.1 and is composed of 13 exons that encode a protein (tryptophan 5-hydroxylase 2) of 490 amino acids

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A study demonstrated that hyperglycemia induces excess ROS production from mononuclear cells, which subsequently triggers the release of tumor necrosis factor- (TNF-) (105)

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doi: 10.1007/S40520-020-01616-X 216 FissiSGoriERomoliniA

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