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In animals with hormonal imbalance, the area of the adrenal gland that usually produces cortisol is incapable of reacting to the ACTH, so that the levels of cortisol remain low
doi: 10.1186/s12974-021-02078-2
This may be related to the fact that overweight and obese PCOS women often exhibit more significant insulin resistance and oxidative stress imbalance [61, 62]
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