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Their conclusion was that, MDMA and psilocybin may show promise in highly selected populations but only where these medicines are administered in closely clinically supervised settings and with intensive professional support. From here, the ACMS will consider the review at their next meeting on 3rd November 2021, with the Delegates decision to be made public in the first week of December

The mechanism(s) may reflect greater stimulation of GLP-1 from the distal gut resulting from a reduction in proximal intestinal glucose absorption, inhibition of bile acid resorption, and/or alterations in the gut microbiota [56]

However, secondary patents covering formulations and dosing methods extend protection through 2031-2033 depending on the specific product