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It based its decision on the results from the The company states that the trial found that Victoza led to: a 22% reduction in cardiovascular death compared with a placebo a 12% lower risk of non-fatal heart attack an 11% risk reduction of non-fatal strokes Trulicity (dulaglutide) In 2020 the FDA approved Trulicity (dulaglutide) for the reduction of major adverse cardiovascular events (MACE) in adults with type 2 diabetes who have established cardiovascular disease or multiple cardiovascular risk factors

The proposed mechanism is that GLP-1 receptor agonists may delay gastric emptying, thereby prolonging lamotrigine absorption

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