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The brain ranks high in this hierarchy, being able to maintain relatively high selenoprotein expression under Se deficiency (Solovyev, 2015
Proteomics 19 (18), e1800311
At the same time, it also possesses a highly flexible high-affinity iron transport system that can switch different uptake strategies by sensing changes in host microenvironment iron concentrations, adapting to both commensal and pathogenic states (Mamouei et al., 2017)
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