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5, 6 DR targets whole-body metabolism, impacting hormones, metabolic substrates and molecular signaling pathways that have a role in metabolic disorders such as obesity and T2D
Obesity can be caused by unbalance between energy intake and energy expenditure [4]
Study limitations include that it was only conducted in a subset of the original 2,539 SURMOUNT-1 participants
New GLP-1 and multi-agonist medications are entering the market, potentially reducing supply pressure on existing drugs
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