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This is why the ENDO research found that greater muscle loss correlated with less improvement in HbA1c

The meta-analysis of the PIONEER and SUSTAIN trials stated, diarrhoea or dehydration can lead to the increase in blood viscosity, semaglutide increases the risk of deep vein thrombosis possibly due to increasing that of diarrhoea. Similarly, the authors said more research is needed on whether the weight loss often experienced while taking semaglutide drugs may increase the risk of DVT, stating, Moreover, whether an increase in deep vein thrombosis is related to a decrease in body weight also needs to be further investigated. People who are taking Ozempic may have patient-specific risk factors that increase the likelihood of developing blood clots

Respiratory Very common (10% or more): Nasopharyngitis (up to 14.5%) Common (1% to 10%): Sinusitis, influenza GLP-1 receptor agonists: Postmarketing reports : Pulmonary aspiration Rare cases of pulmonary aspiration have occurred in patients receiving GLP-1 receptor agonists undergoing elective surgeries/procedures requiring general anesthesia or deep sedation

It is a platform for the development of novel drugs for Type 2 diabetes and obesity