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Elo IT, Luck A, Stokes AC, Hempstead K, Xie W, Preston SH

doi: 10.1371/journal.pone.0021772 33 TakPPBalanescuATseluykoVBojinSDrescherEDairaghiDet al

Additionally, chronic conditions such as HIV and tuberculosis have been implicated in B12 deficiency due to increased metabolic demand and altered absorption mechanisms ( The diagnosis of vitamin B12 deficiency typically relies on low total B12 levels and elevated concentrations of homocysteine (Hcy), as well as levels of transcobalamin-bound B12 (holoTC) and methylmalonic acid (MMA), which serve as functional indicators of cobalamin insufficiency ( Vitamin B12 requirements fluctuate throughout the life course, influenced by metabolic demand and physiological changes

Note that this code is inclusive of laminotomy, facetectomy, foraminotomy, and discectomy