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Within the brain, DSIP is particularly abundant in the hypothalamus, hippocampus, and limbic regions, where it interacts with multiple peptide and non-peptide mediators, including corticotropin-like intermediate peptide (CLIP), adrenocorticotrophic hormone (ACTH), melanocyte-stimulating hormone (MSH), and melanin-concentrating hormone (MCH)

Womack CJ, Saunders MJ, Bechtel MK, Bolton DJ, Martin M, Luden ND et al (2012) The influence of a CYP1A2 polymorphism on the ergogenic effects of caffeine

doi:10.1164/rccm.201201-0130OC Kukwa W, Migacz E, Druc K, Grzesiuk E, Czarnecka AM