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There are several Phase 3 trials evaluating GLP-1s for conditions, such as metabolic dysfunction-associated steatohepatitis (MASH), prediabetes, Alzheimer's disease, diabetic retinopathy and osteoarthritis of the knee (in patients with obesity)
doi: 10.3389/fphar.2026.1795174 Received 24 January 2026 Revised 09 April 2026 Accepted 13 April 2026 Published 30 April 2026 Volume 17 - 2026 Edited by Nabil Eid, IMU University, Malaysia Reviewed by MoezAlIslam Ezzat Faris, Applied Science Private University, Jordan Payal Bhatnagar, International Medical University, Malaysia Gehan El Akabawy, Ajman University, United Arab Emirates Updates Copyright 2026 Ma, Hao, Wang, Qiu, Cao, Deng, Wang, Li, Zhang, Wei, Yao, Gao, Yi, Liu and Li
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It caused the neurons to undergo apoptosis, or programmed cell death
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