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Evidence from alcohol-related and chemical HCC models suggests that alcohol may polarize macrophages toward a pro-tumorigenic M2-like phenotype
10.3748/wjg.v28.i3.310 World J Gastroenterol
It involved doses of up to 25mg/daily and reported the following incidence of side effects in the treatment group [19]: Increased hunger (67%) Joint discomfort (58%) Swelling in the lower limbs (44%) Muscle soreness (33%) These side effects were reported as mild and typically diminished within several months of starting MK-677 administration [19]
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