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A phase 2B clinical trial (HARMONY) revealed that efruxifermin, a bivalent Fc-FGF21 analog, improved hepatic inflammation and fibrosis over 24 weeks in patients with F2 or F3 fibrosis, with an acceptable safety profile, warranting further investigation in phase 3 trials (NCT04767529)
Seck PA, Diagne A, Mohanty S, Wopereis MC (2012) Crops that feed the world 7: rice
retrospectively looked at endpoints of retained food on EGD and found no difference in results for patients using GLP-1RA compared to non-users (95% CI: 0.8720.34)
They may also offer cardiovascular and metabolic benefits
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