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Authors concluded that, in the process of prostate carcinogenesis, activating histone modifications on GSTP1 are lost and subsequently DNA becomes methylated and inaccessible resulting in transcriptional silencing thus demonstrating interplay between histone reprogramming and promoter region methylation (Okino et al., 2007)
Proc Natl Acad Sci USA 98 : 1159811603 Olchovsky D, Song J, Gelato MC, Sherwood J, Spatola E, Bruno JF, Berelowitz M (1993) Pituitary and hypothalamic insulin-like growth factor-I (IGF-I) and IGF-I receptor expression in food-deprived rats
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