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Because tesamorelin stimulates GH production, careful monitoring is advisable when tesamorelin is administered in combination with other drugs known to be metabolized by CYP450 liver enzymes
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In contrast, T2DM may be associated with chronic oxidative stress, exacerbated by dyslipidemia and hypertension, which increase retinal 8-hydroxydeoxyguanosine (8-OHdG), a marker of DNA oxidative damage (63)
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