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vulgaris, which inhibits lipid absorption and transport in the gastrointestinal tract, thus lowering plasma lipid levels and promoting weight loss [47]

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There are no documented human side effects because it has not been tested in people

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A recent meta-analysis and epidemiological studies have shown that affected individuals can have an increased risk of developing diabetes and CVD [2, 4]

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The transmembrane region of RyRs follows a topology very similar to tetrameric voltage-gated channels, with 6 well-defined transmembrane helices per subunit (Fig

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