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The 2020 meta-analysis found a statistically significant reduction in body weight and fat mass, with the best results at doses around 2 grams per day
It is important to understand that the landscape of peptide regulation is mixed
At that point, decisions about adjunctive therapy (if any) are based on individual response data, not assumption
Target trial emulation in EHR/claims + Design an emulated trial comparing semaglutide vs non-SGLT2 comparators with explicit washout, new-user design, and high-dimensional propensity scoring
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