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Pica behavior is a validated endpoint to assess the ability of a compound to induce nausea/malaise in non-vomiting species, as mouse, based on the monitoring of non-nutritive (kaolin) food intake, as an index of gastrointestinal discomfort 43,44
What is L-Carnitine
It is caused by reduced saliva production from GLP-1 receptor effects on salivary glands and from reduced chewing stimulation
However, many patients prefer to begin sooner to avoid a stall in their weight loss journey
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