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At this time, the patient received a diagnosis of ischemic colitis resulting from the use of semaglutide and was recommended not to resume the medication
Not only that, after the small molecule compound Fer-1 inhibited the decrease of glutathione peroxidase 4 (GPX4), the contents of superoxide dismutase (SOD) and glutathione (GSH) increased, malondialdehyde (MDA) decreased, the fluorescence expression of JC-1 polymer increased, the fluorescence of Fe 2+ weakened, and the number of autophagosomes and autolysosomes decreased under transmission electron microscopy.Clear mitochondria and endoplasmic reticulum were observed under high magnification, and the migration and proliferation functions of GC cell lines were also improved.In GC cell lines, ARNTL can activate downstream EGLN2
Proal and Van Elzakker, 2021
Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance (STEP 4)
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