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and (iii) suppressing mTOR/Bax/Bcl-2/caspase-3 signaling activation

Although these changes are generally not clinically significant in healthy individuals, they could pose a greater risk in populations predisposed to metabolic disorders, such as prediabetes or type 2 diabetes

Tirzepatide Dosage Chart (Zepbound/Mounjaro) Tirzepatide is a dual GIP/GLP-1 receptor agonist available as Zepbound (weight management) and Mounjaro (type 2 diabetes)

While not a listed adverse reaction in the SmPC, persistent forceful vomiting can theoretically lead to Mallory-Weiss tearssmall lacerations in the oesophageal mucosa that may bleed